Chaskis C, Brotchi J
Department of Neurosurgery, Erasmus Hospital, U.L.B., Brussels, Belgium.
Neurol Res. 1998 Oct;20(7):597-606. doi: 10.1080/01616412.1998.11740570.
Cavernous angioma (CA) is a hamartomatous hemorrhagic lesion which has received a great deal of attention in recent years due to improvement of neuroimaging with magnetic resonance and heightened clinical awareness. Long considered to be rare, its actual prevalence is now recognized to be of 0.9%. Cavernous angiomas may be multiple, particularly in patients with familial form. It may be associated with a variety of clinical syndromes attributed to focal microhemorrhages or less frequently to gross bleeding. CA are usually diagnosed between the age of 20 and 50 with a highest clinical incidence in the fourth decade. A female predominance is observed in regard to bleeding. The male patients are more at risk for seizures. The recent series of MR imaging confirm that CA even when multiple can be asymptomatic in a significant number of cases. Surgery is the treatment of choice in order to eliminate the risk of hemorrhage and improve the control of seizures. Minimally invasive approaches are now adopted with reduced post-operative morbidity. We report our experience in surgical management of cerebral CA and suggest a classification of the lesions according to surgical accessibility and residual morbidity.
海绵状血管瘤(CA)是一种错构瘤性出血性病变,近年来由于磁共振神经影像学的改进和临床意识的提高而受到广泛关注。长期以来人们认为其较为罕见,但其实际患病率目前已被确认为0.9%。海绵状血管瘤可能是多发的,尤其是在家族性病例中。它可能与多种临床综合征相关,这些综合征归因于局灶性微出血,或较少见的大量出血。海绵状血管瘤通常在20至50岁之间被诊断出来,临床发病率在第四个十年最高。在出血方面观察到女性占优势。男性患者癫痫发作的风险更高。最近一系列的磁共振成像证实,海绵状血管瘤即使是多发的,在相当多的病例中也可能无症状。手术是消除出血风险和改善癫痫控制的首选治疗方法。现在采用微创方法,术后发病率降低。我们报告我们在脑海绵状血管瘤手术治疗方面的经验,并根据手术可及性和残余发病率对病变提出一种分类方法。