Rose D, Sudarsanam A, Padankatti T, Babu P G, John T J
John Scudder Memorial Blood Bank, Department of Clinical Pathology, Christian Medical College & Hospital, Vellore.
Indian J Med Res. 1998 Aug;108:42-4.
To determine the time trend of HIV infection among non-professional blood donors at the Christian Medical College and Hospital, Vellore, the annual HIV prevalence among them for the years 1993-1997 was compared with that of the previous 5 yr. Since confirmed number of HIV positive blood donors is required for calculation of prevalence, the serum samples which were reactive for HIV 1/2 antibody by ELISA, were confirmed by Western blot. The annual prevalence of HIV antibody gradually increased from 1.6 per 1000 in 1988-1989, to 3.8 per 1000 in 1996-1997. The mean tri-annual prevalences for the years 1988-91, 1991-94 and 1994-97 were 1.3, 2.7 and 3.6 per 1000 respectively, suggesting a slow but steady increase in HIV prevalence over time. Our findings provide an insight into the dynamics of HIV infection in the general population of our country, whom the nonprofessional blood donors at our hospital represent.
为了确定基督教医学院和医院（位于韦洛尔）非职业献血者中艾滋病毒感染的时间趋势，将1993 - 1997年期间他们的年度艾滋病毒流行率与之前5年的进行了比较。由于计算流行率需要确诊的艾滋病毒阳性献血者数量，因此通过酶联免疫吸附测定法检测出艾滋病毒1/2抗体呈反应性的血清样本，经免疫印迹法进行确诊。艾滋病毒抗体的年度流行率从1988 - 1989年的每1000人1.6例逐渐上升至1996 - 1997年的每1000人3.8例。1988 - 1991年、1991 - 1994年和1994 - 1997年的三年平均流行率分别为每1000人1.3例、2.7例和3.6例，这表明随着时间的推移，艾滋病毒流行率呈缓慢但稳定的上升趋势。我们的研究结果为我国普通人群中艾滋病毒感染的动态情况提供了见解，而我院的非职业献血者代表了这一普通人群。
