Hansen S E, Gutschik E, Karle A, Rieneck K, Vinicoff P G
H:S Bispebjerg Hospital, reumatologisk afdeling H.
Ugeskr Laeger. 1998 Oct 5;160(41):5935-8.
A retrospective study of 23 patients with spondylodiscitis is reported. Sixteen cases were spontaneous. Five of these were seen in the acute phase with S. aureus grown from the blood. Eleven patients were investigated with CT-guided biopsy of the spine with identification of different microorganisms in eight cases. In four of seven cases of spondylodiscitis after operation for disc herniation coagulase-negative staphyloccoci were grown after CT-guided biopsy. In spontaneous cases pain disappeared and CRP was normalized within a few weeks after treatment with antibiotics, but radiological changes might progress for several months. Antibiotics were given for two to six months, with a mean of 5.1 months in purulent bacterial infections, and all patients were considered cured after this.
报告了一项对23例脊椎椎间盘炎患者的回顾性研究。16例为自发性。其中5例在急性期被发现,血液中培养出金黄色葡萄球菌。11例患者接受了CT引导下的脊柱活检,8例鉴定出不同微生物。在7例椎间盘突出症手术后发生脊椎椎间盘炎的病例中,4例在CT引导下活检后培养出凝固酶阴性葡萄球菌。在自发性病例中,使用抗生素治疗后几周内疼痛消失,CRP恢复正常,但影像学改变可能会持续进展数月。抗生素治疗持续2至6个月,化脓性细菌感染的平均治疗时间为5.1个月,所有患者经此治疗后均被认为治愈。