Young I R, Bell J D, Hajnal J V, Jenkinson G, Ling J
Robert Steiner Magnetic Resonance Unit, Hammersmith Hospital, London, England, UK.
J Magn Reson Imaging. 1998 Sep-Oct;8(5):1114-8. doi: 10.1002/jmri.1880080517.
MR temperature measurements made by the chemical-shift-of-water technique in peripheral muscle of volunteers have produced larger-than-expected coefficients of change and shown significant hysteresis effects as the temperature was cycled, although these effects were not reproduced in the present study. Previous work has suggested that susceptibility effects could be a contributor to the behavior of the chemical shift data. Here, we use proton spectroscopy of muscle in conjunction with temperature cycling to evaluate the relative shifts of the water peak and those of creatine, choline, and lipids. These latter are considered not to have significant temperature coefficients of chemical shift. The results show that these lines remain very stable as the temperature is cycled, suggesting that susceptibility effects are not present in this study. The method offers the possibility that the lines can be used as frequency references if there are any questions about the stability of other moieties.
通过水的化学位移技术在志愿者外周肌肉中进行的磁共振温度测量产生了比预期更大的变化系数，并且在温度循环时显示出显著的滞后效应，尽管本研究中未重现这些效应。先前的工作表明，磁化率效应可能是化学位移数据行为的一个影响因素。在此，我们结合温度循环使用肌肉的质子光谱来评估水峰以及肌酸、胆碱和脂质峰的相对位移。后几种物质被认为没有显著的化学位移温度系数。结果表明，随着温度循环，这些谱线保持非常稳定，这表明本研究中不存在磁化率效应。如果对其他部分的稳定性有任何疑问，该方法提供了这些谱线可作为频率参考的可能性。
