慢性阻塞性肺疾病患者自我测量的呼气峰值流速的精确性和准确性
Precision and accuracy of self-measured peak expiratory flow rates in chronic obstructive pulmonary disease.
作者信息
Murata G H, Lium D J, Busby H K, Kapsner C O
机构信息
Veterans Affairs Medical Center, and the Department of Medicine, University of New Mexico School of Medicine, Albuquerque 87108, USA.
出版信息
South Med J. 1998 Oct;91(10):919-24. doi: 10.1097/00007611-199810000-00005.
BACKGROUND
The precision and accuracy of self-measured peak expiratory flow rates (PEFR) have not been determined for patients with chronic obstructive pulmonary disease (COPD).
METHODS
Twenty-eight male veterans recorded their PEFR twice daily, before and after bronchodilators, for 6 months. Spirometry was also done in the pulmonary function laboratory up to 11 times per patient during the observation period. A 4-week "baseline" was identified for each patient. Baseline coefficients of variation (CV) were calculated for the morning (AM) and evening (PM) PEFR, before (PRE) and after (POST) bronchodilators.
RESULTS
The baseline CVs for AMPRE, AMPOST, PMPRE and PMPOST were 14.9+/-6.9%, 12.6+/-5.6%, 14.9+/-4.8%, and 11.2+/-6.0%, respectively. There were strong correlations between self-measured PEFR and values obtained in the pulmonary function laboratory on the same day.
CONCLUSIONS
Self-measured PFFRs are reasonably precise and accurate in patients with COPD.
背景
慢性阻塞性肺疾病（COPD）患者自行测量的呼气峰值流速（PEFR）的精确度和准确性尚未确定。
方法
28名男性退伍军人每天在使用支气管扩张剂前后记录两次PEFR，持续6个月。在观察期间，每位患者在肺功能实验室最多进行11次肺活量测定。为每位患者确定了一个4周的“基线”。计算了早晨（AM）和晚上（PM）使用支气管扩张剂前（PRE）和使用支气管扩张剂后（POST）的PEFR的基线变异系数（CV）。
结果
AM PRE、AM POST、PM PRE和PM POST的基线CV分别为14.9±6.9%、12.6±5.6%、14.9±4.8%和11.2±6.0%。自行测量的PEFR与同一天在肺功能实验室获得的值之间存在强相关性。
结论
COPD患者自行测量的PFFRs具有合理的精确度和准确性。
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