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小剂量胰岛素持续静脉输注治疗糖尿病酮症酸中毒

[Treatment of diabetic ketoacidosis by continuous venous infusion of small insulin doses].

作者信息

Koeva L, Koev D, Hikolova V, Sirakova V, Gerov P

出版信息

Vutr Boles. 1978;17(3):100-4.

PMID:97866
Abstract

The authors treated 60 patients with diabetic ketoacidosis by continuous venous drop insulin infusion with 8 U every hour during the first six hours and after the sixth hour--20 U every three hours. Rehydration was performed with physiological serum in case of glycemia over 200 mg% and with 5% glucose serum in glycemia under 200 mg%. The patients were led out of ketoacidosis in approximately 9 hours and 36 minutes, the blood sugar diminution being slow and gradual, without hypoglycemic incidence. The average total insulin dose used was 72 U. The authors recommend that method for the practice with a view to its simplicity, safety and high effectiveness.

摘要

作者对60例糖尿病酮症酸中毒患者进行治疗,最初6小时持续静脉滴注胰岛素,每小时8单位,6小时后每3小时20单位。血糖超过200mg%时用生理血清补液,血糖低于200mg%时用5%葡萄糖血清补液。患者在约9小时36分钟内纠正酮症酸中毒,血糖下降缓慢且呈渐进性,无低血糖发生。平均总胰岛素用量为72单位。作者推荐该方法用于临床实践,因其简便、安全且高效。

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