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人胎盘组织中的镉和锌浓度。

Cadmium and zinc concentrations in human placentas.

作者信息

Fiala J, Hrubá D, Rézl P

机构信息

Institute of Preventive Medicine, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

出版信息

Cent Eur J Public Health. 1998 Aug;6(3):241-8.

PMID:9787929
Abstract

Cadmium and zinc levels in placentae of 688 women who delivered their children in two university hospitals in Brno and in the regional hospital in Znojmo during January-June 1992 were determined using AAS analytical method. Average value of zinc (54.6 micrograms/g) and cadmium (18.02 ng/g) concentrations found out in our file are in accord with those ones reported in literature. Individual differences in zinc contained in placentae occur uniformly. Very low concentrations prevail for cadmium; values exceeding 100 ng/g of dry basis are sporadic only. Zinc vs. cadmium concentrations values in placenta are mutually positively correlated [correlation coefficient (factor) r = +0.13, p < 0.001]. Cadmium content in placenta depends on mothers' age and it is significantly higher in older women. No changes in zinc contained in the placental tissue depending on mothers' age were found out. The mutual ratio of zinc vs. cadmium content in a placental tissue is significantly decreased in older mother (23.8 in older women, 41.2 in younger women, p < 0.01).

摘要

1992年1月至6月期间,在布尔诺的两家大学医院以及兹诺伊莫地区医院分娩的688名妇女的胎盘镉和锌水平,采用原子吸收光谱分析法(AAS)进行了测定。我们记录中发现的锌(54.6微克/克)和镉(18.02纳克/克)浓度的平均值与文献报道的一致。胎盘中锌的个体差异均匀出现。镉的浓度极低;超过干重100纳克/克的值仅为零星出现。胎盘中锌与镉的浓度值呈正相关[相关系数(因子)r = +0.13,p < 0.001]。胎盘中的镉含量取决于母亲的年龄,年龄较大的女性中镉含量明显更高。未发现胎盘组织中的锌含量随母亲年龄而变化。年龄较大的母亲胎盘组织中锌与镉含量的相互比例显著降低(老年女性为23.8,年轻女性为41.2,p < 0.01)。

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