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一种测定人胎盘组织中镉含量的分析方法。

An analytical procedure for the determination of cadmium in human placentae.

作者信息

van Hattum B, de Voogt P, Copius Peereboom J W

出版信息

Int J Environ Anal Chem. 1981;10(2):121-33. doi: 10.1080/03067318108071537.

DOI:10.1080/03067318108071537
PMID:7298258
Abstract

Cadmium was determined in human placental tissue by flameless atomic absorption spectrometry (AAS). Several sampling, homogenizing and decomposition procedures were tested with regard to their suitability for flameless AAS. Main criteria involved recovery, representativity contamination, accuracy and precision. Analysis of biological reference materials yielded results in agreement with reported certified values or grand means. A sampling strategy was developed based on expected placental distribution patterns of the metal. The sampling method used appeared to be satisfactorily representative of the organ as a whole. During 1978 and 1979 placentae were collected from mothers living in the Amsterdam area in the Netherlands. Mean placental cadmium levels of smokers (66 +/- 33 ng/g dry weight) appeared to be slightly elevated compared to those of non-smokers (51 +/- 20 ng/g).

摘要

采用无火焰原子吸收光谱法(AAS)测定人胎盘组织中的镉。针对几种采样、匀浆和分解程序对无火焰AAS的适用性进行了测试。主要标准包括回收率、代表性、污染、准确性和精密度。对生物参考物质的分析结果与报告的认证值或总体均值一致。根据金属在胎盘中的预期分布模式制定了采样策略。所采用的采样方法似乎能令人满意地代表整个器官。1978年至1979年期间,从荷兰阿姆斯特丹地区的母亲那里收集了胎盘。吸烟者的胎盘镉平均水平(66±33纳克/克干重)似乎比不吸烟者(51±20纳克/克)略高。

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引用本文的文献

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Environ Health Perspect. 2012 Oct;120(10):1369-77. doi: 10.1289/ehp.1204952. Epub 2012 May 16.
2
A study of the distribution of aluminium in human placental tissues based on alkaline solubilization with determination by electrothermal atomic absorption spectrometry.基于碱溶解-电热原子吸收光谱法测定人胎盘组织中铝的分布研究。
Metallomics. 2010 Sep;2(9):621-7. doi: 10.1039/c0mt00010h. Epub 2010 Aug 17.
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Light and electron microscopic investigation of the rat placenta after cadmium administration during pregnancy.
孕期给予镉后大鼠胎盘的光镜和电镜观察
Anat Embryol (Berl). 1988;178(4):345-51. doi: 10.1007/BF00698665.