Mason B J, Kocsis J H, Melia D, Khuri E T, Sweeney J, Wells A, Borg L, Millman R B, Kreek M J
Laboratory of the Biology of Addictive Diseases, Rockefeller University, New York, NY, USA.
J Addict Dis. 1998;17(3):75-89. doi: 10.1300/J069v17n03_07.
Diagnosing comorbid psychiatric disorders in methadone maintained patients may help to identify subgroups with different outcomes and needs for treatment. In this study, 75 methadone maintenance clinic patients in treatment longer than 30 days were assessed with the Addiction Severity Index, Global Assessment Scale and Mini-Mental Status Exam, and were interviewed for DSM-III-R psychiatric diagnosis using the computerized Diagnostic Interview Schedule. Psychiatric diagnoses were prevalent in the sample with depression, phobic disorders, antisocial personality and generalized anxiety the most common. Both number of DSM-III-R diagnoses and severity of psychopathology were correlated with outcome measures such as concurrent drug abuse, family-social problems and employment status.
诊断接受美沙酮维持治疗患者的共病精神障碍，可能有助于识别出具有不同预后情况及治疗需求的亚组。在本研究中，对75名接受美沙酮维持治疗且治疗时间超过30天的患者，使用成瘾严重程度指数、总体评估量表和简易精神状态检查表进行了评估，并使用计算机化诊断访谈表对其进行访谈以确定DSM-III-R精神疾病诊断。精神疾病诊断在样本中很常见，其中抑郁症、恐惧症、反社会人格和广泛性焦虑最为常见。DSM-III-R诊断的数量和精神病理学的严重程度均与诸如同时存在的药物滥用、家庭-社会问题和就业状况等预后指标相关。
