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养老院居民下呼吸道感染的死亡率。一项基于社区的前瞻性试点研究。

Mortality from lower respiratory infection in nursing home residents. A pilot prospective community-based study.

作者信息

Mehr D R, Zweig S C, Kruse R L, Popejoy L, Horman D, Willis D, Doyle M E

机构信息

Department of Family and Community Medicine, Sinclair School of Nursing, University of Missouri-Columbia 65212, USA.

出版信息

J Fam Pract. 1998 Oct;47(4):298-304.

PMID:9789516
Abstract

BACKGROUND

Lower respiratory infections (LRI) are an important cause of morbidity, mortality, and hospitalization of nursing home residents, yet treatment recommendations have primarily been based on the minority who are hospitalized. We sought to prospectively evaluate risk factors for mortality from LRI in community nursing home residents.

METHODS

We studied residents of 10 central Missouri nursing homes (910 beds) from January 1994 to September 1994. Attending physicians authorized nurse evaluations of ill residents who showed symptoms of an LRI. Those residents who met the study definition of LRI received a more detailed assessment and follow ups at 30 and 90 days.

RESULTS

The 231 evaluations identified 141 LRIs in 121 individuals. Sixteen (11%) residents died within 30 days of evaluation. The most important univariate predictor of 30-day mortality was severe activities of daily living (ADL) dependency (relative risk = 8.8, 95% confidence interval, 2.55-30.1). Several other clinical and laboratory findings were also significant predictors. In multivariable logistic regression, ADL dependency, respiratory rate, and pneumonia on chest radiograph independently predicted mortality; the model showed good discriminating ability (c = .83).

CONCLUSIONS

For nursing home residents with LRI, ADL dependency is an important mortality predictor. Further research with a larger sample should lead to a useful prediction rule for outcome from nursing home-acquired LRI.

摘要

背景

下呼吸道感染(LRI)是疗养院居民发病、死亡和住院的重要原因,但治疗建议主要基于少数住院患者。我们试图前瞻性评估社区疗养院居民LRI死亡的危险因素。

方法

我们研究了1994年1月至1994年9月密苏里州中部10家疗养院(910张床位)的居民。主治医生授权护士对出现LRI症状的患病居民进行评估。那些符合LRI研究定义的居民在30天和90天时接受了更详细的评估和随访。

结果

231次评估在121名个体中确定了141例LRI。16名(11%)居民在评估后30天内死亡。30天死亡率最重要的单变量预测因素是严重的日常生活活动(ADL)依赖(相对风险=8.8,95%置信区间,2.55 - 30.1)。其他一些临床和实验室检查结果也是重要的预测因素。在多变量逻辑回归中,ADL依赖、呼吸频率和胸部X光片上的肺炎独立预测死亡率;该模型显示出良好的辨别能力(c =.83)。

结论

对于患有LRI的疗养院居民,ADL依赖是一个重要的死亡率预测因素。对更大样本的进一步研究应能得出一个有用的疗养院获得性LRI预后预测规则。

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J Fam Pract. 1998 Oct;47(4):298-304.
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