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盐酸赛庚啶作为过敏性猫止痒剂的应用观察

Observations on the use of cyproheptadine hydrochloride as an antipruritic agent in allergic cats.

作者信息

Scott D W, Rothstein E, Beningo K E, Miller W H

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.

出版信息

Can Vet J. 1998 Oct;39(10):634-7.

PMID:9789674
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1539454/
Abstract

Cyproheptadine hydrochloride was administered to 20 presumed or proven allergic cats to determine its efficacy in controlling pruritus. Each cat received 2 mg, orally, every 12 h. The pruritus was satisfactorily controlled in 9 cats. Side effects were seen in 8 cats, and included polyphagia, sedation, vocalization, affectionate behavior, and vomiting.

摘要

给20只疑似或确诊为过敏的猫服用盐酸赛庚啶,以确定其控制瘙痒的效果。每只猫每12小时口服2毫克。9只猫的瘙痒得到了满意控制。8只猫出现了副作用,包括多食、嗜睡、发声、亲昵行为和呕吐。

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引用本文的文献

1
An open clinical trial on the efficacy of cetirizine hydrochloride in the management of allergic pruritus in cats.一项关于盐酸西替利嗪治疗猫过敏性瘙痒疗效的开放性临床试验。
Can Vet J. 2012 Jan;53(1):47-50.

本文引用的文献

1
Disposition of cyproheptadine in cats after intravenous or oral administration of a single dose.
Am J Vet Res. 1998 Jan;59(1):79-81.
2
Therapy for feline dermatoses.猫皮肤病的治疗
Vet Clin North Am Small Anim Pract. 1995 Jul;25(4):981-1005. doi: 10.1016/s0195-5616(95)50138-x.
3
Medical management of allergic pruritus in the cat, with emphasis on feline atopy.猫过敏性瘙痒的药物治疗,重点是猫特应性皮炎。
J S Afr Vet Assoc. 1993 Jun;64(2):103-8.
4
Clemastine fumarate as an antipruritic agent in pruritic cats: results of an open clinical trial.富马酸氯马斯汀作为瘙痒猫的止痒剂:一项开放临床试验的结果
Can Vet J. 1994 Aug;35(8):502-4.
5
Cyproheptadine-induced attenuation of type-I immediate-hypersensitivity reactions of airway smooth muscle from immune-sensitized cats.
Am J Vet Res. 1995 Jan;56(1):109-15.
6
Efficacy of chlorpheniramine maleate for management of pruritus in cats.
J Am Vet Med Assoc. 1990 Jul 1;197(1):67-70.
7
Failure of cyproheptadine hydrochloride as an antipruritic agent in allergic dogs: results of a double-blinded, placebo-controlled study.
Cornell Vet. 1992 Jul;82(3):247-51.