Descarries L
Département de pathologie, Faculté de médecine, Université de Montréal, Québec, Canada.
J Physiol Paris. 1998 Jun-Aug;92(3-4):215-20. doi: 10.1016/s0928-4257(98)80013-2.
Recent ultrastructural data demonstrate the largely asynaptic character of the cholinergic innervation in many regions of adult rat brain. These data favour the hypothesis of a diffuse transmission/modulation by acetylcholine in the CNS and, by way of consequence, that of a persistent, low level of acetylcholine in the extracellular space.