Sax K W, Strakowski S M, Keck P E
Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267-0559, USA.
Schizophr Res. 1998 Oct 9;33(3):151-5. doi: 10.1016/s0920-9964(98)00067-x.
This study examined changes in attentional performance in patients with schizophrenia during the 2 months after initiating treatment with quetiapine fumarate. Prior to treatment, attentional performance in patients with schizophrenia (n = 10) was significantly (p < 0.01) worse than in matched controls (n = 12). During treatment with quetiapine, performance in patients with schizophrenia improved, and by 2 months, did not differ significantly from that of the controls. These results suggest that quetiapine produces a significant improvement in attentional functioning in patients with schizophrenia.
本研究检测了富马酸喹硫平治疗2个月期间精神分裂症患者注意力表现的变化。治疗前，10例精神分裂症患者的注意力表现显著（p < 0.01）差于12例匹配的对照组。在喹硫平治疗期间，精神分裂症患者的表现有所改善，到2个月时，与对照组无显著差异。这些结果表明，喹硫平可显著改善精神分裂症患者的注意力功能。
