Aylward G W, Chang T S, Pautler S E, Gass J D
Bascom Palmer Eye Institute, Miami, Fla, USA.
Arch Ophthalmol. 1998 Oct;116(10):1337-41. doi: 10.1001/archopht.116.10.1337.
To provide long-term follow-up information on a large series of patients with choroidal osteoma.
Review of patients with a diagnosis of choroidal osteoma who had been examined at the Bascom Palmer Eye Institute, Miami, Fla, or known to one of us (J.D.M.G.). Information was obtained from hospital medical records or by a questionnaire sent to referring ophthalmologists. Life-table analysis was used to study the loss of vision and development of choroidal neovascularization.
We followed up 36 patients, 31 (89%) were female, mean age, 21 years (range, 5-54 years) for a mean of 10 years (range, 2-22 years). Growth was observed for 9 (41%) of 22 well-documented osteomas. The probability of loss of visual acuity to 20/200 or worse was 58% by 10 years and 62% by 20 years. The probability of developing choroidal neovascularization was 47% by 10 years and 56% by 20 years. Successful treatment of the choroidal neovascularization with laser photocoagulation was performed for 5 (25%) of 20 patients.
Most patients with choroidal osteomas maintain good vision in at least 1 eye, but they have a high risk of developing choroidal neovascularization. When this occurs, only a minority can be successfully treated with laser photocoagulation.
提供关于大量脉络膜骨瘤患者的长期随访信息。
回顾在佛罗里达州迈阿密市巴斯科姆·帕尔默眼科研究所接受检查或为我们其中一人（J.D.M.G.）所知的诊断为脉络膜骨瘤的患者。信息从医院病历中获取或通过发送给转诊眼科医生的问卷获得。采用寿命表分析来研究视力丧失和脉络膜新生血管形成情况。
我们随访了36例患者，其中31例（89%）为女性，平均年龄21岁（范围5 - 54岁），平均随访时间10年（范围2 - 22年）。在22例记录完整的骨瘤中，观察到9例（41%）有生长。到10年时视力降至20/200或更差的概率为58%，到20年时为62%。到10年时发生脉络膜新生血管形成的概率为47%，到20年时为56%。20例患者中有5例（25%）通过激光光凝成功治疗了脉络膜新生血管形成。
大多数脉络膜骨瘤患者至少一只眼保持良好视力，但他们发生脉络膜新生血管形成的风险很高。当这种情况发生时，只有少数患者能通过激光光凝成功治疗。
