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结膜下罗阿丝虫感染:手术后治愈的血清学确认

Subconjunctival infection with Dirofilaria repens: serological confirmation of cure following surgery.

作者信息

Ruiz-Moreno J M, Bornay-Llinares F J, Prieto Maza G, Medrano M, Simón F, Eberhard M L

机构信息

División de Oftalmología y IOA, Universidad Miguel Hernández, Alicante, Spain.

出版信息

Arch Ophthalmol. 1998 Oct;116(10):1370-2. doi: 10.1001/archopht.116.10.1370.

DOI:10.1001/archopht.116.10.1370
PMID:9790641
Abstract

Cases of zoonotic dirofilariasis infection, caused by Dirofilaria repens, occur widely throughout European, African, Middle Eastern, and Asian countries. The reports of this infection in humans in Spain are limited, and we herein report the case of a 43-year-old man from Elche (Alicante), Spain, who was seen with acute hyperemic reactivity of the temporal limbus of the right eye. A large nematode was visualized on examination and the intact worm was surgically removed. The parasite was identified as a mature but infertile female D repens. The level of serum antibodies against D repens was monitored for 6 months after surgery using immunoenzymatic assays. Serological results confirmed, as expected, the presence of a single worm and the parasitological cure after the surgical removal of the parasite. To our knowledge, this is the fourth autochthonous case of D repens infecting humans in Spain and also the first autochthonous case of subconjunctival localization.

摘要

由匐行恶丝虫引起的人畜共患恶丝虫病感染病例在欧洲、非洲、中东和亚洲国家广泛存在。西班牙关于人类感染此病的报告有限,在此我们报告一例来自西班牙阿利坎特省埃尔切市的43岁男性病例,该患者右眼颞侧角膜缘出现急性充血反应。检查时发现一条大型线虫,完整的虫体通过手术取出。该寄生虫被鉴定为一条成熟但不育的雌性匐行恶丝虫。术后6个月使用免疫酶测定法监测血清中抗匐行恶丝虫抗体水平。血清学结果正如预期,证实了单条虫体的存在以及手术摘除寄生虫后的寄生虫学治愈情况。据我们所知,这是西班牙第四例人类感染匐行恶丝虫的本土病例,也是第一例结膜下定位的本土病例。

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Arch Ophthalmol. 1998 Oct;116(10):1370-2. doi: 10.1001/archopht.116.10.1370.
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