Maksimov D G, Domracheva M V
Kosm Biol Aviakosm Med. 1976 Sep-Oct;10(5):52-7.
Central and peripheral circulation was studied rheographically in 6 test subjects during a 30-day bed rest experiment and in 9 test subjects during a 49-day bed rest. The bed rested subjects were kept in a head-down position at an angle of --4 degrees. At an early stage of the experiments the cardiac output and stroke volume increased, the total peripheral resistance decreased, the tone of major regional vessels decreased and that of small vessels increased. During the 3rd-7th weeks the changes were just the opposite: cardiac output and stroke volume decreased, the total peripheral resistance increased the tone of major regional vessels increased and that of small vessels decreased. At the end of the bed rest experiment the cardiac output and stroke volume increased and the tone of regional vessels changed accordingly. Circulation parameters returned to the pretest level, at least, 3-4 weeks after the end of the best rest experiments.
在一项为期30天的卧床休息实验中，对6名受试者进行了血流图检查以研究其中心和外周循环；在一项为期49天的卧床休息实验中，对9名受试者进行了同样的检查。卧床休息的受试者保持头部向下倾斜4度的姿势。在实验早期，心输出量和每搏输出量增加，总外周阻力降低，主要区域血管的张力降低，小血管的张力增加。在第3至7周期间，变化情况正好相反：心输出量和每搏输出量降低，总外周阻力增加，主要区域血管的张力增加，小血管的张力降低。在卧床休息实验结束时，心输出量和每搏输出量增加，区域血管的张力也相应改变。至少在卧床休息实验结束后3至4周，循环参数恢复到测试前水平。
