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[结直肠上皮性肿瘤中核仁组织区诊断及预后意义评估的统计学分析]

[Statistical analysis in the assessment of diagnostic and prognostic significance of nucleolus organizer regions in colorectal epithelial neoplasms].

作者信息

Turbin D A, Perevoshchikov A G

机构信息

N. N. Blokhin Cancer Research Centre, Moscow.

出版信息

Arkh Patol. 1998 Jul-Aug;60(4):19-23.

PMID:9791691
Abstract

Different parametric and non-parametric methods of statistics have been analysed in the assessment of diagnostic and prognostic value of nucleolar organizer regions (NORs) in epithelial colorectal neoplasms. NORs activity was studied in adenomas and so-called "small" adenocarcinomas invading only mucosa and submucosa. The data obtained show that NORs activity can help in the differential diagnosis of adenomas and in situ adenocarcinomas of the colorectum. Results of NORs evaluation depend primarily on the statistical methods used.

摘要

在评估结直肠上皮性肿瘤中核仁组织区(NORs)的诊断和预后价值时,已对不同的参数统计方法和非参数统计方法进行了分析。研究了腺瘤以及仅侵犯黏膜和黏膜下层的所谓“小”腺癌中的NORs活性。所获得的数据表明,NORs活性有助于结直肠腺瘤与原位腺癌的鉴别诊断。NORs评估结果主要取决于所使用的统计方法。

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