Iuele R, Gallippi G, Giacchetto C
Servizio di Anatomia ed Istologia Patologica, Ospedale Civile dell'Annunziata, USSL 9, Cosenza.
Pathologica. 1994 Oct;86(5):525-7.
Argyrophilie technique to identify nucleolar organizer regions (NORs) applied in formalin-fixed paraffin sections of thyroid tissue allow us to reveal NORs as block dots in the nuclei of cells. In the present study the relationship between number of NORs and cellular activation emphasize significant statistical data: it was found that the number of AgNORs in malignant thyroid lesions significantly exceeded those of benign thyroid lesions. This objective assessment associated with easily method show an advantage in thyroid diagnostic histopathology an adjunct to routine methods.
用于鉴定核仁组织区(NORs)的嗜银技术应用于甲状腺组织的福尔马林固定石蜡切片,使我们能够将NORs显示为细胞核中的块状小点。在本研究中,NORs数量与细胞活化之间的关系强调了显著的统计数据:发现甲状腺恶性病变中的AgNORs数量显著超过良性甲状腺病变。这种与简便方法相关的客观评估在甲状腺诊断组织病理学中显示出优势,可作为常规方法的辅助手段。