Efimenko V N
Lik Sprava. 1998 Jul-Aug(5):122-6.
Acute disseminated encephalomyelitis (ADEM) has been studied in a series of 30 children (16 girls, 14 boys) who ranged from 1.5 to 15 years old versus 24 pediatric patients (12 girls, 9 boys) aged 4-15 years with diagnosed disseminated sclerosis (DS). Conducted in the above series were the following investigations: computerized tomography, magnetic resonance imaging, recording of visual evoked potentials, indices for cellular and humoral immunity. ADEM, as distinct from DS, was marked by: an acute onset; the presence of general infectious symptoms together with general cerebral ones; involvement into the process of not only white matter but also of nuclear formations and peripheral nervous system; unidirectional course resulting in residual events. In 16 children a clear distinction was seen between ADEM and DS, while the rest of this pediatric population (n = 14) who had residual events presenting as pyramidal syndrome, might well develop DS in later life. Additional differential-diagnostic tests employed in the above study were found to be of little informative value.
对30名年龄在1.5至15岁的儿童（16名女孩，14名男孩）进行了急性播散性脑脊髓炎（ADEM）的研究，并与24名年龄在4至15岁、已确诊为播散性硬化症（DS）的儿科患者（12名女孩，9名男孩）进行对比。对上述两组患者进行了以下检查：计算机断层扫描、磁共振成像、视觉诱发电位记录、细胞免疫和体液免疫指标检测。与DS不同，ADEM的特点为：起病急；伴有全身感染症状和全脑症状；不仅白质受累，核团及周围神经系统也受累；病程单向性，可遗留后遗症。16名儿童的ADEM与DS有明显区别，而该儿科人群中的其他儿童（n = 14）遗留有锥体综合征等后遗症，很可能在以后的生活中发展为DS。上述研究中采用的其他鉴别诊断检查被发现信息价值不大。
