Osoba A O
Afr J Med Med Sci. 1977 Sep;6(3):125-32.
A sero epidemiological study involving 5009 individuals resident in the two largest cities (Ibadan and Benin) in the Western Region of Nigeria has been carried out, using the LGVCFT to determine the presence of LGV antibodies. These individuals come from various population groups and social classes (i.e. blood donors, antenatal clinic patients, general out-patients, venereal diseases clinic patients and prostitutes). Among the 3638 subjects tested in Ibadan, the seroreactivity rates ranged from 5.3% to 11.5%, while of the 1371 in Benin, the seroreactivity ranged from 7.3% to 18.3%. The seroreactivity rates confirm previous suspicion that there is a considerable reservoir of infection among the female population both in normal women and in prostitutes. While the value of LGVCFT as an epidemiological tool in the estimation of latent or active infection in a community has been substantiated, a puzzling variation in the endemicity of the LGV agent, even within the same region, has been observed. It is suggested that routine testing of blood donors and antenatal women with LGVCFT such as done with serological tests for syphilis should be carried out in tropical countries where LGV is endemic.
在尼日利亚西部地区两个最大的城市（伊巴丹和贝宁），对5009名居民开展了一项血清流行病学研究，采用淋巴肉芽肿性腹股沟炎补体结合荧光试验（LGVCFT）来确定是否存在淋巴肉芽肿性腹股沟炎（LGV）抗体。这些个体来自不同人群和社会阶层（即献血者、产前门诊患者、普通门诊患者、性病门诊患者和妓女）。在伊巴丹接受检测的3638名受试者中，血清反应率在5.3%至11.5%之间，而在贝宁的1371名受试者中，血清反应率在7.3%至18.3%之间。血清反应率证实了之前的怀疑，即在正常女性和妓女的女性人群中存在大量感染源。虽然LGVCFT作为一种流行病学工具在评估社区中潜伏或活动性感染方面的价值已得到证实，但即使在同一地区内，也观察到LGV病原体的地方性存在令人费解的差异。建议在LGV为地方病的热带国家，对献血者和孕妇进行常规的LGVCFT检测，就如同梅毒血清学检测那样。
