Sitzia J, Haddrell V, Rice-Oxley M
Worthing Hospital NHS Trust, Sussex, UK.
Clin Rehabil. 1998 Oct;12(5):389-94. doi: 10.1191/026921598675167321.
To ascertain whether or not an inpatient multidisciplinary treatment programme for patients with Parkinson's disease or multiple sclerosis resulted in a measurable change in patients' health-related quality of life (HRQL).
Assessments of HRQL were made one week before adm ssion and approximately one month post discharge.
Six-bed Neurological Rehabilitation Unit at Worthing Hospital on the south coast of England.
Fifty-eight patients with Parkinson's disease and 33 patients with multiple sclerosis.
All patients received an individually adapted, multidisciplinary rehabilitation programme. The programmes lasted from 5 to 10 days.
HRQL scores on the Nottingham Health Profile Part 1 (NHP-1).
Overall post-treatment NHP-1 scores were significantly better than overall pretreatment scores for both the Parkinson's group (z= 2.6, p <0.01) and the multiple sclerosis group (z = 2.1, p <0.05). Sixty-four per cent of patients perceived an overall improvement. The strongest improvement was in 'physical mobility' in the multiple sclerosis group (z = 3.0, p <0.01) and in 'emotional reactions' in the Parkinson's group (z = 2.9, p <0.01).
These results suggest that the multidisciplinary inpatient approach in neurological rehabilitation has identifiable short-term benefits for the majority of patients. A randomized trial with longer follow-up is required to confirm this.
确定针对帕金森病或多发性硬化症患者的住院多学科治疗方案是否能使患者的健康相关生活质量（HRQL）产生可测量的变化。
在入院前一周和出院后约一个月进行HRQL评估。
英格兰南海岸沃辛医院的六张床位神经康复科。
58例帕金森病患者和33例多发性硬化症患者。
所有患者均接受个性化的多学科康复方案。这些方案持续5至10天。
诺丁汉健康量表第1部分（NHP - 1）的HRQL评分。
帕金森病组（z = 2.6，p <0.01）和多发性硬化症组（z = 2.1，p <0.05）治疗后的总体NHP - 1评分均显著优于治疗前的总体评分。64%的患者感觉总体状况有所改善。改善最明显的方面，在多发性硬化症组是“身体活动能力”（z = 3.0，p <0.01），在帕金森病组是“情绪反应”（z = 2.9，p <0.01）。
这些结果表明，神经康复中的多学科住院治疗方法对大多数患者有明显的短期益处。需要进行一项随访时间更长的随机试验来证实这一点。
