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约旦的糖尿病和糖耐量受损:患病率及相关危险因素

Diabetes and impaired glucose tolerance in Jordan: prevalence and associated risk factors.

作者信息

Ajlouni K, Jaddou H, Batieha A

机构信息

National Centre for Diabetes, Endocrine and Genetic Diseases, Amman, Jordan and the University of Science and Technology, Irbid.

出版信息

J Intern Med. 1998 Oct;244(4):317-23. doi: 10.1046/j.1365-2796.1998.00369.x.

DOI:10.1046/j.1365-2796.1998.00369.x
PMID:9797495
Abstract

OBJECTIVES

To study the prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) and their risk factors in Jordan.

DESIGN

A cross-sectional study in four Jordanian communities was conducted: Sarih in the north, Sikhra in the middle of the country, Mazar in the south and Subha-Subheih in the east. Within each community, a systematic sample of households was selected. All subjects > or =25 years of age within the selected households were invited to participate in the study. A total of 2836 subjects were actually included in the study with an overall response rate of 70.5%(45% in males and 86% in females). World Health Organization criteria were adopted for the diagnosis of DM (fasting plasma glucose > or =7.8 mmol L(-1) or plasma glucose of > or =11.1 mmol L(-1), 2 h after an oral anhydrous glucose load of 75 g) and IGT (fasting plasma glucose <7.8 mmol L(-1)and plasma glucose between 7.8 mmol L(-1) and 11.1 mmol L(-1), 2 h after an oral glucose load of 75 g).

RESULTS

The overall prevalence of DM was 13.4%: 14.9% in males and 12.5% in females. IGT was found in 9.8% of the study population: 9.0% in males and 10.3%, in females. Factors independently related to DM using stepwise logistic regression analysis were sex, age, family history of DM, hypertension, hypercholesterolaemia (HC), and hypertriglyceridaemia (HTG).

CONCLUSION

Diabetes mellitus and IGT are common among adult Jordanians. Considering the high prevalence of this sickness makes it imperative to formulate a national plan to face this disease and its complications.

摘要

目的

研究约旦糖尿病(DM)和糖耐量受损(IGT)的患病率及其危险因素。

设计

在约旦的四个社区开展了一项横断面研究,这四个社区分别是北部的萨里赫、中部的锡赫拉、南部的马扎尔和东部的苏卜哈 - 苏卜海。在每个社区内,选取了系统抽样的家庭。邀请所选家庭中所有年龄大于或等于25岁的受试者参与研究。共有2836名受试者实际纳入研究,总体应答率为70.5%(男性为45%,女性为86%)。采用世界卫生组织的标准诊断DM(空腹血糖大于或等于7.8 mmol/L或口服75 g无水葡萄糖负荷后2小时血糖大于或等于11.1 mmol/L)和IGT(空腹血糖小于7.8 mmol/L且口服75 g葡萄糖负荷后2小时血糖在7.8 mmol/L至11.1 mmol/L之间)。

结果

DM的总体患病率为13.4%:男性为14.9%,女性为12.5%。在9.8%的研究人群中发现了IGT:男性为9.0%,女性为10.3%。使用逐步逻辑回归分析与DM独立相关的因素为性别、年龄、DM家族史、高血压、高胆固醇血症(HC)和高甘油三酯血症(HTG)。

结论

糖尿病和IGT在约旦成年人中很常见。鉴于这种疾病的高患病率,制定一项国家计划来应对这种疾病及其并发症势在必行。

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