伴有涉及1q21的“跳跃易位”的多发性骨髓瘤的不寻常表现。病例报告及文献复习
Unusual presentation of multiple myeloma with "jumping translocation" involving 1q21. A case report and review of the literature.
作者信息
Keung Y K, Yung C, Wong J W, Shah F, Cobos E, Tonk V
机构信息
Division of Oncology/Hematology, Cytogenetic Laboratory, Texas Tech University Health Sciences Center, Lubbock, USA.
出版信息
Cancer Genet Cytogenet. 1998 Oct 15;106(2):135-9. doi: 10.1016/s0165-4608(97)00316-6.
PMID:9797778
Abstract
We describe a case of multiple myeloma with unusual manifestations consisting of cutaneous xanthomatosis, temporal arteritis, retinal vasculitis with a complex karyotype, and a "jumping translocation" involving 1q21. The literature of cytogenetic studies of multiple myeloma and of jumping translocation is reviewed.
摘要
我们描述了一例多发性骨髓瘤，其具有不寻常的表现，包括皮肤黄瘤病、颞动脉炎、伴有复杂核型的视网膜血管炎以及涉及1q21的“跳跃易位”。本文对多发性骨髓瘤的细胞遗传学研究及跳跃易位的文献进行了综述。
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