Ehler R, Meyer P, Hartwich G
Med Klin. 1976 Oct 8;71(41):1740-3.
In a 61 year-old female patient with Hodgkin's disease treated with cytotoxic drugs and radiation therapy acute undifferentiated leukemia developed 10 years later. The possibility of a carcinogenic effect of the cytotoxic and actinic therapy is discussed. Leukemia complicating the course of Hodgkin's disease must be considered an independent disease and not a iatrogenic transformation of a preexisting lesion.
一名61岁患有霍奇金病的女性患者接受了细胞毒性药物和放射治疗,10年后发生了急性未分化白血病。讨论了细胞毒性和光化疗法的致癌作用可能性。霍奇金病病程中并发的白血病必须被视为一种独立疾病,而非先前存在病变的医源性转化。