Xu B, Rantakallio P, Järvelin M R
Unit of Environmental Epidemiology, National Public Health Institute, Kuopio, Finland.
Epidemiology. 1998 Nov;9(6):662-5.
We followed 11,355 children born in 1966 up to the age of 24 years to investigate the impact of birthweight on long-term outcomes of death and development. As expected, low-birthweight (LBW, 1500-2,499 gm) children showed a higher risk of death than normal-birthweight (NBW, > or =2,500 gm) children before the age of 15 years. Rate ratios for LBW children ranged from 25 for the first week of life to 2.5 for ages 5-14 years. Rate ratios of very-low-birthweight (VLBW, <1,500 gm) children for the first year of life were 10 times higher than those of LBW children. Similarly, for the first 14 years of life, surviving LBW children experienced a higher risk of being hospitalized as well as staying in hospitals for over 2 weeks if they were hospitalized. The LBW children still had a higher risk of receiving sick pensions at the age of 24 years.
我们对1966年出生的11355名儿童进行了追踪，直至他们24岁，以研究出生体重对死亡和发育等长期结果的影响。正如预期的那样，低体重（LBW，1500 - 2499克）儿童在15岁之前的死亡风险高于正常体重（NBW，≥2500克）儿童。低体重儿童的比率从出生后第一周的25降至5 - 14岁时的2.5。极低体重（VLBW，<1500克）儿童在出生后第一年的比率比低体重儿童高10倍。同样，在生命的前14年中，存活的低体重儿童住院风险更高，并且如果住院，住院时间超过2周的风险也更高。低体重儿童在24岁时领取病残抚恤金的风险仍然较高。
