Cooke R W I
Neonatal Unit, Liverpool Women's Hospital, Crown Street, Liverpool L8 7SS, UK.
Arch Dis Child. 2004 Mar;89(3):201-6. doi: 10.1136/adc.2003.030197.
Children born very preterm and able to attend mainstream schools have been shown to have a high prevalence of behavioural, minor motor, and learning difficulties. It is not clear whether these problems persist into adulthood, impacting on lifestyle and quality of life.
A previously studied cohort of very low birth weight infants born between 1980 and 1983, together with term classmate controls, were assessed at age 19-22 years using a postal questionnaire. The questionnaire included the SF-36 to assess quality of life, a social activities scale, a lifestyle questionnaire, the Hospital Anxiety and Depression Scale, and questions on current height, weight, health, family structure, and education and occupation.
Of the 138 preterm and 163 term controls in the cohort, 79 preterm and 71 term returned questionnaires. Quality of life was assessed as similar on six of eight domains of the SF-36. Social activities were also similar. Preterms drank less alcohol, used fewer illicit drugs, but smoked as often. Rates for sexual intercourse were similar, although preterms had more children. Preterms were shorter than controls and were less satisfied with their appearance. They were more likely to use a regular prescription medicine. Fewer were or had been in higher education, and some remained unemployed.
The problems experienced by very preterm infants at school appear to influence lifestyle and health, but not perceived quality of life in early adulthood.
研究表明,极早产且能进入主流学校就读的儿童存在行为、轻微运动及学习困难的比例很高。目前尚不清楚这些问题是否会持续至成年期,进而影响生活方式和生活质量。
对1980年至1983年间出生的极低出生体重婴儿及其足月出生的同班同学对照组进行一项前期研究,在他们19至22岁时通过邮寄问卷进行评估。问卷包括用于评估生活质量的SF-36量表、社交活动量表、生活方式问卷、医院焦虑抑郁量表,以及关于当前身高、体重、健康状况、家庭结构、教育程度和职业的问题。
该队列中有138名早产儿和163名足月出生的对照组,其中79名早产儿和71名足月出生的对照组返回了问卷。在SF-36量表的八个领域中的六个领域中,两组的生活质量评估结果相似。社交活动情况也相似。早产儿饮酒较少,使用非法药物较少,但吸烟频率相同。两组的性交率相似,不过早产儿生育的子女更多。早产儿比对照组矮,对自己的外表不太满意。他们更有可能使用常规处方药。接受高等教育或曾经接受高等教育的早产儿较少,一些人仍处于失业状态。
极早产婴儿在学校所经历的问题似乎会影响成年早期的生活方式和健康状况,但不会影响其对生活质量的感知。