Hooley R
Institute of Arable Crops Research (IACR), Department of Agricultural Sciences, University of Bristol, UK.
Philos Trans R Soc Lond B Biol Sci. 1998 Sep 29;353(1374):1425-30. doi: 10.1098/rstb.1998.0297.
Plants perceive and respond to a profusion of environmental and endogenous signals that influence their growth and development. The G-protein signalling pathway is a mechanism for transducing extracellular signals that is highly conserved in a range of eukaryotes and prokaryotes. Evidence for the existence of G-protein signalling pathways in higher plants is reviewed, and their potential involvement in plant hormone signal transduction evaluated. A range of biochemical and molecular studies have identified potential components of G-protein signalling in plants, most notably a homologue of the G-protein coupled receptor superfamily (GCR1) and the G alpha and G beta subunits of heterotrimeric G-proteins. G-protein agonists and antagonists are known to influence a variety of signalling events in plants and have been used to implicate heterotrimeric G-proteins in gibberellin and possibly auxin signalling. Antisense suppression of GCR1 in Arabidopsis leads to a phenotype which supports a role for this receptor in cytokinin signalling. These observations suggest that higher plants have at least some of the components of G-protein signalling pathways and that these might be involved in the action of certain plant hormones.
植物能够感知并响应大量影响其生长和发育的环境及内源信号。G蛋白信号通路是一种转导细胞外信号的机制，在一系列真核生物和原核生物中高度保守。本文综述了高等植物中存在G蛋白信号通路的证据，并评估了它们在植物激素信号转导中的潜在作用。一系列生化和分子研究已经确定了植物中G蛋白信号的潜在组成部分，最显著的是G蛋白偶联受体超家族（GCR1）的一个同源物以及异源三聚体G蛋白的Gα和Gβ亚基。已知G蛋白激动剂和拮抗剂会影响植物中的多种信号事件，并已被用于表明异源三聚体G蛋白参与赤霉素信号转导，可能还参与生长素信号转导。拟南芥中GCR1的反义抑制导致一种表型，这支持了该受体在细胞分裂素信号转导中的作用。这些观察结果表明，高等植物至少具有G蛋白信号通路的一些组成部分，并且这些部分可能参与某些植物激素的作用。
