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[莫拉雷脑膜炎。一种具有特征性表现的罕见疾病]

[Mollaret's meningitis. A rare disease with a characteristic presentation].

作者信息

Ruhnau B K, Laub M S, Permin H

机构信息

H:S Rigshospitalet, RHIMA Centret, epidemiafdeling M.

出版信息

Ugeskr Laeger. 1998 Oct 12;160(42):6083-4.

PMID:9800513
Abstract

We report a case of a 72-year-old woman, who within a six-year period had four episodes of Mollaret's meningitis. Lumbar punctures during each episode revealed moderate leukocytosis with large mononuclear cells. Characteristic manifestations and differential diagnosis are briefly reviewed. There is no established therapy for Mollaret's meningitis. Extensive investigations failed to reveal a specific cause of this disease, although there is some evidence for infection caused by Herpes simplex-virus.

摘要

我们报告一例72岁女性患者,在六年时间内发生了四次莫拉雷脑膜炎发作。每次发作时腰椎穿刺显示有中度白细胞增多,并伴有大量单核细胞。本文简要回顾了其特征性表现及鉴别诊断。目前尚无针对莫拉雷脑膜炎的确立疗法。尽管有一些证据表明是由单纯疱疹病毒感染所致,但广泛检查未能揭示该疾病的具体病因。

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Mollaret's meningitis and herpes simplex virus type 1.莫拉雷脑膜炎与1型单纯疱疹病毒
N Engl J Med. 1992 Mar 26;326(13):893-4. doi: 10.1056/NEJM199203263261313.
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Herpes simplex virus type 2 (Mollaret's) meningitis: a case report.单纯疱疹病毒 2 型(Mollaret)脑膜炎:一例报告。
Int J Infect Dis. 2009 Nov;13(6):e476-9. doi: 10.1016/j.ijid.2009.01.003. Epub 2009 Mar 28.

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