Harrison W J, Rankin K C
Mpilo Central Hospital and King George VI Rehabilitation Centre, Bulawayo, Zimbabwe.
J R Coll Surg Edinb. 1998 Oct;43(5):328-32.
The results of surgical treatment of 15 children with osteogenesis imperfecta in Bulawayo, Zimbabwe are reviewed. A total of 23 self-expanding and 27 fixed-length rods were used. Outcome was measured in terms of mobility status, growth, incidence of refracture, need for reoperation, and complications. Eight of the children improved their mobility status over the course of treatment. Self-expanding rods appeared to confer more benefit to growth than fixed-length rods. Refracture was more common in bones splinted with fixed-length rods and more often necessitated revision surgery in these bones. The complication rate was high in all cases, but the complications associated with outgrown fixed-length rods were a particular problem. The 15 children benefited from surgical treatment. The self-expanding rods performed better than fixed-length rods in reducing the number of surgical interventions. They also appear to facilitate growth. The self-expanding rods may be used to good effect in appropriate centres in the developing world.
本文回顾了津巴布韦布拉瓦约15名成骨不全患儿的外科治疗结果。共使用了23根自膨胀棒和27根定长棒。通过活动状态、生长情况、再骨折发生率、再次手术需求及并发症等方面来衡量治疗效果。8名患儿在治疗过程中活动状态得到改善。自膨胀棒似乎比定长棒对生长更有益。使用定长棒固定的骨骼再骨折更常见,且这些骨骼更常需要翻修手术。所有病例的并发症发生率都很高,但与定长棒生长过度相关的并发症是一个特别的问题。这15名患儿从外科治疗中受益。自膨胀棒在减少手术干预次数方面比定长棒表现更好。它们似乎也有助于生长。自膨胀棒在发展中国家的合适医疗中心可能会取得良好效果。