Campo P, León-Carrión J, Domínguez-Roldán J M, Revuelta M, Murillo-Cabezas F
Facultad de Psicología, Universidad de Sevilla, España.
Rev Neurol. 1998 Oct;27(158):616-25.
Epilepsy is one of the most common neurological disorders, affecting about one percent of the world population. Pharmacological treatment fails in one-third of these patients. Surgical intervention has become an accepted treatment option for those patients with seizure disorders that are refractory to conventional therapies. Cortical resection and callosotomy are the most widely accepted methods of surgical intervention. A prerequisite for success in this type of surgical intervention is the preoperative clinical assessment of the epilepsy surgery candidate.
This paper examines the current uses of neuropsychological assessment in an epilepsy surgery program. Several areas are addressed for discussion with respect to the contributions of neuropsychological assessment: the preoperative evaluation of the epilepsy surgery candidates, including the clinical examination of language and memory functions during the Wada test; the neuropsychological changes that result from surgery and the predictive role of neuropsychology in these areas, and prediction for seizure control following surgery.
Assessment of cognitive functions is an important component of the preoperative evaluation of the epilepsy surgery candidate, and is needed in order to obtain complete diagnostic information.
癫痫是最常见的神经系统疾病之一，影响着全球约1%的人口。其中三分之一的患者药物治疗无效。对于那些对传统疗法难治的癫痫患者，手术干预已成为一种被认可的治疗选择。皮质切除术和胼胝体切开术是最广泛接受的手术干预方法。这类手术成功的一个先决条件是对癫痫手术候选人进行术前临床评估。
本文探讨了神经心理学评估在癫痫手术项目中的当前应用。就神经心理学评估的贡献而言，有几个方面有待讨论：癫痫手术候选人的术前评估，包括在Wada试验期间对语言和记忆功能的临床检查；手术引起的神经心理学变化以及神经心理学在这些方面的预测作用，以及对术后癫痫控制的预测。
认知功能评估是癫痫手术候选人术前评估的重要组成部分，为获得完整的诊断信息所必需。
