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利比亚东北部的胆囊癌

Gall bladder cancer in north eastern Libya.

作者信息

Sarma N H, Ramesh K, Gahukamble L D, Fituri O M, Mangal D K

机构信息

Department of Pathology, Al Arab Medical University, Benghazi, Libya.

出版信息

East Afr Med J. 1998 Jul;75(7):417-21.

PMID:9803634
Abstract

OBJECTIVE

Assessment of gall bladder cancer among cholecystectomy specimens.

DESIGN

Retrospective study of all cholecystectomy specimens coupled with data from clinical oncology department.

SETTING

Department of Pathology and Department of Clinical Oncology, Al Arab Medical University, Benghazi, Libya.

SUBJECT

Gall bladder cancer among cholecystectomies and the pattern of survival of these patients.

MATERIAL

Histopathology records available on all cholecystectomies performed between 1982 and 1997. Data available on staging and survival of cancer patients from clinical oncology upto 1996.

RESULTS

Eighty nine cases of gall bladder cancer were found out of 7352 cholecystectomies performed over a period of 16 years. It was found more commonly in females with a mean age of 58.1 years. It was also observed that the incidence in males above 60 years was almost equal to that of females. Gall bladder cancer when primarily detected by the pathologist in cholecystectomy specimens removed for symptomatic cholelithiasis, was mostly in stage I. Most of the patients in stage III-IV cancer died within one year whereas most of the stage I cancer patients survived more than two years.

CONCLUSION

Simple cholecystectomy is strongly advised in women above 50 years of age and in men above 60 years of age with symptomatic cholelithiasis.

摘要

目的

评估胆囊切除术标本中的胆囊癌情况。

设计

对所有胆囊切除术标本进行回顾性研究,并结合临床肿瘤学部门的数据。

地点

利比亚班加西阿拉伯医学大学病理学系和临床肿瘤学系。

研究对象

胆囊切除术中的胆囊癌以及这些患者的生存模式。

材料

1982年至1997年间所有胆囊切除术的组织病理学记录。截至1996年临床肿瘤学中关于癌症患者分期和生存情况的数据。

结果

在16年期间进行的7352例胆囊切除术中,发现了89例胆囊癌。该疾病在女性中更为常见,平均年龄为58.1岁。还观察到60岁以上男性的发病率几乎与女性相等。当病理学家在因有症状胆结石而切除的胆囊切除术标本中首次检测到胆囊癌时,大多处于I期。III - IV期癌症的大多数患者在一年内死亡,而大多数I期癌症患者存活超过两年。

结论

强烈建议对50岁以上有症状胆结石的女性和60岁以上有症状胆结石的男性进行单纯胆囊切除术。

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