Rubinow D R, Schmidt P J, Roca C A
Behavioral Endocrinology Branch, National Institute of Mental Health, Bethesda, MD 20892-1276, USA.
Psychopharmacol Bull. 1998;34(3):289-90.
Mood disturbances have been identified in association with changes in levels of reproductive hormones. The use of hormonal measures in the diagnosis of reproductive endocrine-related mood disorders is highly variable, ranging from necessary in perimenopausal depression to irrelevant in premenstrual syndrome. This article describes our view of the use of hormonal measures for diagnostic and research purposes in perimenopausal depression and premenstrual syndrome. We suggest that the understanding of these disorders lies in as yet unidentified contextual factors rather than in hormonal excesses or deficiencies.
情绪障碍已被确定与生殖激素水平的变化有关。在诊断与生殖内分泌相关的情绪障碍时，激素检测方法的使用差异很大，从围绝经期抑郁症诊断中的必要手段到经前综合征诊断中的无关手段。本文阐述了我们对于在围绝经期抑郁症和经前综合征的诊断及研究中使用激素检测方法的观点。我们认为，对这些疾病的理解在于尚未明确的背景因素，而非激素过多或不足。
