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颌骨间叶性软骨肉瘤。4例报告。

Mesenchymal chondrosarcoma of the jaws. Report of four cases.

作者信息

Lockhart R, Menard P, Martin J P, Auriol M, Vaillant J M, Bertrand J C

机构信息

Service de Stomatologie et Chirurgie Maxillo-Faciale, Groupe hospitalier Pitié-Salpêtrière, Paris, France.

出版信息

Int J Oral Maxillofac Surg. 1998 Oct;27(5):358-62. doi: 10.1016/s0901-5027(98)80065-9.

Abstract

Mesenchymal chondrosarcoma (MCS), described in 1959 by Lichtenstein & Bernstein, is a very rare malignant tumour. Only 46 cases have been previously reported in the jaws. Over a period of 30 years, four chondrosarcomas of mesenchymal type (of which one has already been published in 1987 with a three-month follow up) were treated in our department. Two patients have been followed for more than 17 years, of whom one has died of an intracranial extension and the other is still alive after surgical treatment of numerous recurrences and metastases. The two others are tumour-free with a follow up of 18 months and 11 years respectively. Histological, epidemiological and clinical features and treatment of MCS are discussed relevant to the data published in the literature.

摘要

间叶性软骨肉瘤(MCS)由利希滕斯坦和伯恩斯坦于1959年首次描述,是一种极为罕见的恶性肿瘤。此前仅有46例颌骨间叶性软骨肉瘤的病例报道。在30年的时间里,我们科室共治疗了4例间叶型软骨肉瘤(其中1例已于1987年发表,随访期为3个月)。两名患者的随访时间超过了17年,其中一名患者因肿瘤颅内扩散死亡,另一名患者在经历多次复发和转移的手术治疗后仍然存活。另外两名患者分别随访了18个月和11年,目前均无肿瘤复发迹象。本文结合文献中发表的数据,对间叶性软骨肉瘤的组织学、流行病学、临床特征及治疗方法进行了讨论。

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