Hajji L, Alami M, Ghannam R, Sadeli M, el Moktadir N, Benjelloun H, Benomar M, Benomar M
Ligue nationale de lutte contre les maladies cardiovasculaires, CHU Ibn Sina, Rabat, Maroc.
Arch Mal Coeur Vaiss. 1998 Sep;91(9):1183-6.
The authors present the case of a 42 year old patient admitted for surgery of massive aortic regurgitation. Investigation of this patient who had no significant cardiovascular risk factors, showed diffuse and accelerated atherosclerosis (severe stenosis at the origin of both subclavian arteries at both superficial femoral arteries). Tertiary syphilis with neurological involvement and aortitis was confirmed by histological examination (peroperative biopsy of the aortic wall). This case is unusual due to the association of early atherosclerosis with tertiary syphilis and raises the question of the causality of syphilis in the generation of these atherosclerotic lesions.
作者报告了一例42岁因重度主动脉瓣关闭不全入院接受手术的患者。对该无明显心血管危险因素的患者进行检查发现弥漫性加速动脉粥样硬化（双侧锁骨下动脉起始处及双侧股浅动脉重度狭窄）。经组织学检查（主动脉壁手术活检）确诊为三期梅毒伴神经受累及主动脉炎。该病例因早期动脉粥样硬化与三期梅毒并存而不寻常，并引发了梅毒在这些动脉粥样硬化病变发生过程中因果关系的问题。
