有丝分裂进程中的关卡。
Checkpoints on the road to mitosis.
作者信息
Russell P
机构信息
Dept of Molecular Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
出版信息
Trends Biochem Sci. 1998 Oct;23(10):399-402. doi: 10.1016/s0968-0004(98)01291-2.
PMID:9810229
Abstract
Eukaryotic organisms use cell-cycle checkpoints to ensure that nuclear division is restrained while DNA is undergoing replication or repair. Recent studies of the fission yeast Schizosaccharomyces pombe have illuminated these checkpoint mechanisms. These investigations have connected checkpoint proteins with central elements of the mitotic-control machinery.
摘要
真核生物利用细胞周期检查点来确保在DNA进行复制或修复时，核分裂受到抑制。对裂殖酵母粟酒裂殖酵母的最新研究阐明了这些检查点机制。这些研究将检查点蛋白与有丝分裂控制机制的核心元件联系了起来。
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