Landier W
School of Nursing, University of California, Los Angeles, USA.
J Pediatr Oncol Nurs. 1998 Oct;15(4):195-206. doi: 10.1177/104345429801500402.
Children undergoing treatment for cancer often receive agents that put them at risk for ototoxicity. Platinum-based chemotherapy, aminoglycoside antibiotics, loop diuretics, and radiotherapy are all capable of inducing inner ear damage, which may result in significant sensorineural hearing loss. Frequent audiological monitoring is necessary for the early detection of changes in hearing thresholds. Age-appropriate modification of audiological testing is essential to obtain accurate results and provide maximum comfort for pediatric patients. When hearing loss is identified promptly, consideration may be given to treatment modification and/or early intervention with hearing aids and other assistive devices. The consequences of hearing loss differ depending on the developmental stage of the child at the time that hearing loss occurs. Language acquisition may be affected in very young children, whereas educational and psychosocial concerns are paramount for the older child. The pediatric oncology nurse is instrumental in assisting the child and family who are coping with hearing loss related to cancer treatment.
接受癌症治疗的儿童经常会使用一些使其面临耳毒性风险的药物。铂类化疗药物、氨基糖苷类抗生素、袢利尿剂和放射治疗都有可能导致内耳损伤，进而可能导致严重的感音神经性听力损失。频繁进行听力监测对于早期发现听力阈值变化很有必要。根据年龄适当调整听力测试对于获得准确结果以及为儿科患者提供最大程度的舒适感至关重要。当听力损失被及时发现时，可以考虑调整治疗方案和/或尽早使用助听器及其他辅助设备进行干预。听力损失的后果因听力损失发生时儿童的发育阶段而异。对于幼儿来说，语言习得可能会受到影响，而对于年龄较大的儿童，教育和心理社会问题则至关重要。儿科肿瘤护士在帮助应对与癌症治疗相关听力损失的儿童及其家庭方面发挥着重要作用。
