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乙二醇中毒

Ethylene glycol poisoning.

作者信息

Vale J A, Bluett N H, Widdop B

出版信息

Postgrad Med J. 1976 Sep;52(611):598-602. doi: 10.1136/pgmj.52.611.598.

Abstract

Although an uncommon cause of death in Great Britain, ethylene glycol poisoning is potentially serious in that renal and cardiopulmonary failure and central nervous system dysfunction can occur when doses of the order of 100 ml or more are ingested. A case is described in which a child who swallowed approximately 100 ml of ethylene glycol was treated by prolonged peritoneal dialysis. In addition, measures were taken to correct a marked acidosis. Substantial amounts of ethylene glycol were removed by the dialysis fluid and the child made a complete physical and mental recovery.

摘要

尽管乙二醇中毒在英国并非常见死因,但它具有潜在的严重性,因为当摄入100毫升或更多剂量时,可能会发生肾衰竭、心肺衰竭和中枢神经系统功能障碍。本文描述了一例病例,一名吞食了约100毫升乙二醇的儿童接受了长时间的腹膜透析治疗。此外,还采取了措施纠正明显的酸中毒。透析液清除了大量的乙二醇,该儿童在身体和精神上完全康复。

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Ethylene glycol poisoning.乙二醇中毒
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引用本文的文献

5
Treatment of ethylene glycol poisoning with peritoneal dialysis.用腹膜透析治疗乙二醇中毒。
Br Med J (Clin Res Ed). 1982 Feb 20;284(6315):557. doi: 10.1136/bmj.284.6315.557.

本文引用的文献

3
Renal failure secondary to ethylene glycol intoxication.乙二醇中毒继发的肾衰竭。
JAMA. 1960 Jul 16;173:1210-3. doi: 10.1001/jama.1960.03020290036007.
5
Toxic hazards. Deaths from permanent antifreeze ingestion.毒性危害。因误食长效防冻液致死。
N Engl J Med. 1959 Dec 17;261:1296-7. doi: 10.1056/NEJM195912172612514.
6
The nephrotoxic lesion of ethylene glycol.乙二醇的肾毒性损伤
Ann Intern Med. 1957 Mar;46(3):611-9. doi: 10.7326/0003-4819-46-3-611.
8
Ethylene glycol toxicity.
Am J Clin Pathol. 1966 Jan;45(1):46-50. doi: 10.1093/ajcp/45.1.46.

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