Pourquié O
Laboratoire de Génétique et de Physiologie du Développement (LGPD), CNRS-INSERM-Université de la Méditerranée-AP de Marseille, France.
Curr Opin Neurobiol. 1998 Oct;8(5):665-70. doi: 10.1016/s0959-4388(98)80097-4.
Developmental clocks are hypothetical embryonic time-measuring devices--some are run by oscillators, whereas others depend on rate-limiting processes. Their existence has been deduced from recent studies of the timing of the midblastula transition, the opening of the Hox cluster during organogenesis, and oligodendrocyte progenitor differentiation; however, the mechanisms underlying their function remain largely unknown.
发育时钟是一种假设的胚胎计时装置——有些由振荡器驱动，而另一些则依赖于限速过程。它们的存在是从最近对囊胚中期转换时间、器官发生过程中Hox基因簇的开启以及少突胶质细胞祖细胞分化的研究中推断出来的；然而，其功能背后的机制在很大程度上仍然未知。
