Koshcheenko K A, Borman E A, Bychkova G G
Prikl Biokhim Mikrobiol. 1976 Sep-Oct;12(5):650-3.
The process of transformation of microcystalline acetate cortisone by two mycobacteria (Mycobacterium album and Mycobacterium globiforme) has been studied. Optimal conditions for the process have been established: amount of biomass of both cultures, concentration of the initial substrate and required concentration of the surfactant--antifoamsilane. The anzymic activity of the cultures reaches maximum if the following three requirements are met: utilization of cells separated from the medium, substrate in the microcrystalline state and surfactant of the antifoamsilane type.
对两种分枝杆菌（白色分枝杆菌和球状分枝杆菌）对醋酸微晶皮质酮的转化过程进行了研究。已确定该过程的最佳条件：两种培养物的生物量、初始底物浓度和所需的表面活性剂——消泡硅烷浓度。如果满足以下三个条件，培养物的酶活性达到最大值：利用从培养基中分离出的细胞、微晶状态的底物和消泡硅烷类型的表面活性剂。
