微晶表氢化可的松及其21 - 乙酸酯的微生物学1,2 - 脱水反应
Microbiological 1,2-dehydration of microcrystalline epihydrocortisone and its 21-acetate.
作者信息
Borman E A, Koshcheenko K A, Sokolova L V
出版信息
Biol Bull Acad Sci USSR. 1978 Nov-Dec;5(6):747-9.
PMID:756290
Abstract
A method is described for obtaining epiprednisolone and its 21-acetate by means of microbiological 1,2-dehydration by a culture of Mycobacterium globiforme 193. The substrate, epihydrocortisone or its 21-acetate, is added in the form of a microcrystalline suspension at a concentration of 25-100 g/liter medium.
摘要
描述了一种通过球状分枝杆菌193培养物进行微生物1,2-脱水来获得表氢化泼尼松及其21-乙酸酯的方法。底物，即表氢化可的松或其21-乙酸酯，以微晶悬浮液的形式添加，浓度为25-100克/升培养基。
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