Zhou Z F, Zhang Y S, Wang Y M
Department of Digestion, First Affiliated Hospital of Kunming Medical College.
Zhonghua Liu Xing Bing Xue Za Zhi. 1997 Feb;18(1):18-21.
Under cluster sampling, an early serum essay of helicobacterpylori (Hp) infection among 1084 healthy people, was carried out. Out of them, 325 among the Yi and Han Nationalities at Yunxian County of Yunnan Province were given a simultaneous test of anti-HAV IgG. The results were as follows: overall Hp infection rate was 51.1%; no difference of the infection was observed between the Yis and the Hans; the prevalence of Hp antibody went up with age; Higher rates were detected among those who drank river water or unboiled-water than among those who drank tap water, well water or boiled water, from poultry raisers than from non-poultry raisers and with drug abusers than with non-drug abusers. Hp infection showed a parallel relation to HAV infection. Finally, seven main epidemic factors were sifted from multi-factor logistic analysis namely source of drinking water, drinking habit, chicken-raising, pig-keeping, dog-breeding, drug-abusing and consumption of garlic. All these findings suggested that drinking water was an important vehicle of Hp infection. Our research data seems to have lend support to both fecal- oral transmission viewpoint and the hypothesis that Hp infection derives from animals. Frequent intake of garlic may serve as an agent in long-term prevention of Hp infection among people in this area.
采用整群抽样方法，对1084名健康人群进行了幽门螺杆菌（Hp）感染的早期血清学检测。其中，对云南省云县彝族和汉族的325人同时进行了抗甲型肝炎病毒（HAV）IgG检测。结果如下：Hp总体感染率为51.1%；彝族和汉族之间的感染情况无差异；Hp抗体阳性率随年龄增长而升高；饮用河水或生水的人群感染率高于饮用自来水、井水或开水的人群，饲养家禽者高于非饲养家禽者，吸毒者高于非吸毒者。Hp感染与HAV感染呈平行关系。最后，通过多因素logistic分析筛选出7个主要流行因素，即饮用水源、饮水习惯、养鸡、养猪、养狗、吸毒和大蒜食用情况。所有这些发现表明，饮用水是Hp感染的重要传播媒介。我们的研究数据似乎支持了粪-口传播观点以及Hp感染源自动物的假说。经常食用大蒜可能是该地区人群长期预防Hp感染的一种手段。
