Luo T Y, Pan N Q
Department of Infetious Disease, Guiyang Medical College.
Zhonghua Liu Xing Bing Xue Za Zhi. 1997 Feb;18(1):37-9.
Pathogenetic significance of major risk factors to primary hepatoma among young people was investigated through a case-control study. The analysis of single-factor showed that there was close relationship between HBV infection, family history of hepatoma and the primary hepatocellular carcinoma among young people, with an OR 25.3. Multiple-factorial analysis indicated that the effect of HBV infection far exceeded other risk factors in the pathogenesis of primary hepatoma, suggesting the HBV infection might be a major cause of primary hepatoma among young people.
通过病例对照研究探讨了年轻人原发性肝癌主要危险因素的致病意义。单因素分析显示，HBV感染、肝癌家族史与年轻人原发性肝细胞癌密切相关，比值比（OR）为25.3。多因素分析表明，HBV感染在原发性肝癌发病机制中的作用远远超过其他危险因素，提示HBV感染可能是年轻人原发性肝癌的主要原因。
