Zhao N, Yu S, Sun W M
School of Public Health, Shanghai Medical University.
Zhonghua Liu Xing Bing Xue Za Zhi. 1994 Apr;15(2):90-3.
This paper evaluates the combined effect of HBsAg, drinking water and aflatoxin B1 (AFB1) on the primary hepatocellular carcinoma (PHC) in a case-control study which was carried out in Fusui, Guangxi. We used relative risk model (from subadditive to supermultiplicative) to fit the relationship. The results showed that the combined effect of HBsAg infection and drinking pond-ditch water is nearly multiplicative, and the combined effect of HBsAg infection and AFB1 intake as well as drinking pond-ditch water and AFB1 intake were nearly additive.
本文在广西扶绥开展的一项病例对照研究中，评估了乙肝表面抗原（HBsAg）、饮用水及黄曲霉毒素B1（AFB1）对原发性肝细胞癌（PHC）的联合作用。我们使用相对风险模型（从次相加到超相乘）来拟合这种关系。结果显示，HBsAg感染与饮用坑塘水的联合作用接近相乘，HBsAg感染与AFB1摄入以及饮用坑塘水与AFB1摄入的联合作用接近相加。
