Cheng X S, Li J Z, Zhang Z X
Fu Wai Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Liu Xing Bing Xue Za Zhi. 1997 Oct;18(5):282-5.
This paper tends to evaluate the effects of comprehensive prevention and treatment in COPD and cor pulmonale in the communities. A Randomized cohort with stratified design was undertaken in the rural areas with hundred thousand population in Beijing municipality, Lianning and Hubei Provinces, from spring 1992 to spring 1995.
(1) the rates to all stratified populations under management were 85.6% among those with high risk, 87.8% among COPD and 83.6% among cor pulmonale, respectively. (2) The levels of KAB were raised more significantly in most intervention group than in control group which up +9.6% to +33.6% and -5.8% to +32.6%, respectively. (3) Comparisons between the two groups revealed: 1. Number of cigarette smokers who smoked more than before increased (20.1% vs 17.8%) but with no statistical significance. 2. The rate of smoking cessation went higher (15.5% vs. 11.3%, P < 0.01). 3. New high risk subjects were reduced (2.8% vs 3.9%, P < 0.01). 4. Number of new cor pulmonale patients decreased (19.9% vs 22.6%, P > 0.05) and mortality rate lowered (4.34% vs 4.78%, P > 0.05).
preliminary results indicates that the active intervention is effective in reducing COPD and cor pulmonale among population at high risk in communities. However, it is necessary to point out that COPD and cor pulmonale are both having chronic nature which calls for patient and continuous efforts.
本文旨在评估社区中慢性阻塞性肺疾病(COPD)和肺心病综合防治的效果。1992年春至1995年春,在北京、辽宁和湖北省的10万人口农村地区进行了一项分层设计的随机队列研究。
(1)所有分层人群的管理率分别为:高危人群85.6%,COPD患者87.8%,肺心病患者83.6%。(2)大多数干预组的知识、态度和行为(KAB)水平比对照组提高得更显著,分别提高了+9.6%至+33.6%和 -5.8%至+32.6%。(3)两组比较显示:1. 吸烟量比以前增加的吸烟者人数有所增加(20.1%对17.8%),但无统计学意义。2. 戒烟率更高(15.5%对11.3%,P<0.01)。3. 新的高危对象减少(2.8%对3.9%,P<0.01)。4. 新的肺心病患者人数减少(19.9%对22.6%,P>0.05),死亡率降低(4.34%对4.78%,P>0.05)。
初步结果表明,积极干预对降低社区高危人群中的COPD和肺心病有效。然而,需要指出的是,COPD和肺心病均具有慢性性质,需要耐心和持续的努力。