Wang Y, Han W, An Y
Yantai Health and Anti-epidemic Station Yantai, Shandong.
Zhonghua Yu Fang Yi Xue Za Zhi. 1997 May;31(3):147-8.
Two hundred and forty-eight blood specimens collected from patients of sporadic acute viral hepatitis were serotyped with enzyme immunoassay (EIA), to study its pathogenic components during non-epidemic seasons of hepatitis A (HA). Results showed that HA accounted for 61.3% of the total sporadic acute hepatitis cases during its non-epidemic seasons, occurred mainly in youngsters and decreased with increase of their age. Hepatitis B (HB) ranked the second and accounted for 26.2%, occurred mainly in the middle-aged and the elderly and its prevalence increased with age. Hepatitis C (HC) accounted for 9.9% and hepatitis E (HE) 22.2% of the total cases, without obvious age difference. Prevalence of hepatitis D (HD) was 12.7%, with a positive rate of hepatitis D antigen (HDAg) of 12%. Superinfection accounted for 18.9%, and the viral hepatitis markers were all negative in 0.8% of the total cases. There was very significant difference in prevalence of HCV-IgG and HEV-IgG between sporadic acute hepatitis patients and blood donors during the same periods. Icterus occurred in 68% of the total cases, 86.8% in HA. Patients of HB complicated with HD were liable to chronicity.
采用酶免疫分析法（EIA）对248份散发型急性病毒性肝炎患者的血标本进行血清分型，以研究甲型肝炎（HA）非流行季节的致病成分。结果显示，HA在其非流行季节的散发型急性肝炎病例中占61.3%，主要发生在年轻人中，并随年龄增长而减少。乙型肝炎（HB）位居第二，占26.2%，主要发生在中年人和老年人中，其患病率随年龄增长而增加。丙型肝炎（HC）占总病例的9.9%，戊型肝炎（HE）占22.2%，无明显年龄差异。丁型肝炎（HD）患病率为12.7%，丁型肝炎抗原（HDAg）阳性率为12%。重叠感染占18.9%，0.8%的总病例中病毒性肝炎标志物均为阴性。散发性急性肝炎患者与同期献血者的HCV-IgG和HEV-IgG患病率存在非常显著差异。68%的总病例出现黄疸，HA中为86.8%。HB合并HD的患者易发展为慢性。
