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黄芪活性成分对活性氧所致人红细胞膜损伤的保护作用

[Protective effect of active components extracted from radix Astragali on human erythrocyte membrane damages caused by reactive oxygen species].

作者信息

Wang D, Shen W, Tian Y, Sun Z, Jiang C, Yuan S

机构信息

Department of Biochemistry, General Hospital of PLA, Beijing.

出版信息

Zhongguo Zhong Yao Za Zhi. 1996 Dec;21(12):746-8, 763.

PMID:9812683
Abstract

A study has been made on the protective activities of active components extracted from Radix Astragali by using reactive oxygen species initiated lipid peroxidation of purified human erythrocyte membrane. The results show that the total flavonoids of Astragalus and total saponins of Astragalus can significantly inhibit the membrane lipid peroxidation generated by O2.-, H2O2 and UV rays, while the total polysaccharide of Astragalus possesses weaker protective activity.

摘要

采用活性氧引发纯化的人红细胞膜脂质过氧化的方法,对黄芪活性成分的保护作用进行了研究。结果表明,黄芪总黄酮和黄芪总皂苷能显著抑制由超氧阴离子自由基、过氧化氢和紫外线引发的膜脂质过氧化,而黄芪总多糖的保护活性较弱。

相似文献

1
[Protective effect of active components extracted from radix Astragali on human erythrocyte membrane damages caused by reactive oxygen species].黄芪活性成分对活性氧所致人红细胞膜损伤的保护作用
Zhongguo Zhong Yao Za Zhi. 1996 Dec;21(12):746-8, 763.
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[Protective effect of total flavonoids of radix Astragali on mammalian cell damage caused by hydroxyl radical].黄芪总黄酮对羟自由基所致哺乳动物细胞损伤的保护作用
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Zhongguo Zhong Yao Za Zhi. 1995 Sep;20(9):558-60, inside backcover.
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引用本文的文献

1
Flavonoids from the Genus Astragalus: Phytochemistry and Biological Activity.黄芪属植物中的黄酮类化合物:植物化学与生物活性。
Pharmacogn Rev. 2016 Jan-Jun;10(19):11-32. doi: 10.4103/0973-7847.176550.
2
A novel antioxidant agent, astragalosides, prevents shock wave-induced renal oxidative injury in rabbits.一种新型抗氧化剂黄芪苷可预防冲击波诱导的兔肾氧化损伤。
Urol Res. 2006 Aug;34(4):277-82. doi: 10.1007/s00240-006-0057-1. Epub 2006 Jun 17.