粉防己碱对野百合碱诱导的大鼠肺动脉高压和右心室肥厚的预防作用
[Preventive effects of tetrandrine on pulmonary hypertension and right ventricular hypertrophy in rats induced by monocrotaline].
作者信息
Jin X, Zhang X, Xing J, Liu K, Wang H
机构信息
Pharmacology Department, China Medical University, Shenyang.
出版信息
Zhongguo Zhong Yao Za Zhi. 1996 Dec;21(12):751-2, 763.
PMID:9812685
Abstract
Pulmonary hypertension and right ventricular hypertrophy in rats were developed 3 weeks after administration of monocrotaline 50 mg/kg i.p. Tetrandrine 10 mg/kg and 15 mg/kg bid p.o. could prevent the above-said effects produced by monocrotaline.
摘要
腹腔注射50mg/kg野百合碱3周后，大鼠出现肺动脉高压和右心室肥厚。口服粉防己碱10mg/kg和15mg/kg，每日2次，可预防野百合碱产生的上述效应。
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