Barinagarrementeria F, Gonzàlez-Duarte A, Miranda L, Cantú C
Stroke Clinic, Stroke Program, Instituto Nacional de Neurología y Neurocirugía, Manuel Velasco Suárez, Tlalpan, Mexico City, Mexico.
Eur Neurol. 1998 Nov;40(4):228-33. doi: 10.1159/000007985.
The aim of this study was to determine the risk factors and mechanism of cerebral infarction in young women.
We evaluated 130 consecutive women younger than 41 years of age with cerebral infarction and compared the risk factors with a control group of 122 healthy, age-matched women.
The leading risk factors in patients with cerebral infarction were migraine (15%), tobacco use (15%), and oral contraceptive (OC) use (12%). Cerebral arteriograms were abnormal in 59% of patients (57 of 96). The causes of cerebral infarction were cardiac embolism in 36%, nonatherosclerotic vasculopathy in 25%, hematologic disorders in 8%, and migraine in 8%. The etiology could not be determined in 23% of patients.
Migraine and OCs are independent risk factors for cerebral infarction in young women. The leading etiologies were rheumatic valve disease and nonatherosclerotic vasculopathy, hematologic disturbances, and migraine were responsible for a few cases.
本研究的目的是确定年轻女性脑梗死的危险因素及机制。
我们评估了130例年龄小于41岁的连续脑梗死女性患者，并将其危险因素与122名年龄匹配的健康女性对照组进行比较。
脑梗死患者的主要危险因素为偏头痛（15%）、吸烟（15%）和口服避孕药（OC）使用（12%）。96例患者中有57例（59%）脑动脉造影异常。脑梗死的病因包括心脏栓塞占36%、非动脉粥样硬化性血管病占25%、血液系统疾病占8%、偏头痛占8%。23%的患者病因无法确定。
偏头痛和口服避孕药是年轻女性脑梗死的独立危险因素。主要病因是风湿性瓣膜病和非动脉粥样硬化性血管病，血液系统紊乱和偏头痛导致少数病例。
