Adams H P, Butler M J, Biller J, Toffol G J
Arch Neurol. 1986 Aug;43(8):793-6. doi: 10.1001/archneur.1986.00520080041017.
We evaluated 144 patients (81 males and 63 females) aged 15 to 45 years who had nonhemorrhagic cerebral infarction. Atherosclerotic cerebral infarction was diagnosed in 38 patients. Potential cardiac causes of cerebral embolism were found in 33 patients. Only three events could be attributed to mitral valve prolapse. Hematologically related disorders were diagnosed in 21 patients, while 38 patients had nonatherosclerotic vasculopathies. Young patients with cerebral infarction are a heterogeneous group. A potential cause can be found in most patients. We found more than 40 possible etiologies among our patients. Mitral valve prolapse apparently is not a common cause of cerebral infarction among young adults. Cerebral infarction should not be ascribed to oral contraceptives or migraine until other possible causes have been eliminated.
我们评估了144例年龄在15至45岁之间的非出血性脑梗死患者（81例男性和63例女性）。38例患者被诊断为动脉粥样硬化性脑梗死。33例患者发现了可能导致脑栓塞的心脏病因。只有3例事件可归因于二尖瓣脱垂。21例患者被诊断为血液学相关疾病，38例患者患有非动脉粥样硬化性血管病变。年轻的脑梗死患者是一个异质性群体。大多数患者都能找到潜在病因。我们在患者中发现了40多种可能的病因。二尖瓣脱垂显然不是年轻成年人脑梗死的常见病因。在排除其他可能病因之前，不应将脑梗死归因于口服避孕药或偏头痛。
