Grigorenko D E
Arkh Anat Gistol Embriol. 1978 Jun;74(6):31-5.
Cell composition of various components (cortical plateau, folliculi and cords) of ileocecal lymph nodes was studied in newborn, 1.5 and 2.5 months of age (2 animals) and in mature (3 animals) monkeys, Papio hamadryas. In histological sections obtained at the level of hilus of the lymph node cellular elements were counted by means of morphometric grid of Glagolev modifoed by S. B. Stefanov. The data obtained were statistically treated. Newborn and mature monkeys have their peculiar cytological profile in every structural component of the lymph node. The lymph nodes in the newborns contain much more reticular cells and young cellular forms (blast forms and large lymphocytes) than mature animals. In the newborns, the number of mitotically deviding cells in the cortical plateau and in folliculi is 6 times and in myelin cords 10 times as great as in mature monkeys. A much greater per cent of plasmatic cells in mature animals suggests their greater immunological activity. Age differences in cell composition of lymph nodes in young and mature monkeys seem to be connected with accumulation of cellular mass and growth of the node in young animals, as well as with general rearrangement of the organism as a whole (in particular with changes in nutrition, intensity of movement, hormonal background).
研究了新生、1.5月龄和2.5月龄（各2只动物）以及成年（3只动物）阿拉伯狒狒回盲部淋巴结各组成部分（皮质平台、滤泡和索）的细胞组成。在淋巴结门水平获取的组织学切片中，借助S. B. 斯特凡诺夫改良的格拉戈列夫形态测量网格对细胞成分进行计数。对所得数据进行统计学处理。新生和成年猴子在淋巴结的每个结构成分中都有其独特的细胞学特征。与成年动物相比，新生动物的淋巴结含有更多的网状细胞和年轻细胞形态（母细胞形态和大淋巴细胞）。在新生动物中，皮质平台和滤泡中有丝分裂细胞的数量是成年猴子的6倍，在髓索中是10倍。成年动物中浆细胞的百分比要高得多，这表明它们具有更强的免疫活性。幼年和成年猴子淋巴结细胞组成的年龄差异似乎与幼年动物细胞质量的积累和淋巴结的生长有关，也与整个机体的总体重新排列有关（特别是与营养、运动强度、激素背景的变化有关）。
